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Network Analysis predicts IRDs
July 18, 2023Structure-based_network_analysis_predicts_mutation Read More
Natural History of RP: new findings
July 18, 2023Natural_history_of_retinitis_pigmentosa_based_on_g-1 Read More
Ocular Trauma during COVID-19 pandemic
July 18, 2023Br-J-Ophthalmol_Halawa_2023 Read More
JAMA Ophthalmol Ramo 2023
June 5, 2023Central Serous Chorioretinopathy and Age-Related Macular Degeneration. Read More
Eric Pierce Proctor Lecture ARVO 2023
May 31, 2023Eric Pierce, MD, PhD received the Proctor Medal at the recent Association for Research in Vision and Ophthalmology (ARVO) meeting in New Orleans. Dr. Pierce is the Chatlos Professor of Ophthalmology and Director of the Ocular Genomics Institute at Harvard Medical School and Mass Eye and Ear. The Proctor Medal is one of the most prestigous... Read More
Racing the Clock and Raising Hope for Usher Syndrome Patients
November 15, 2022Researchers Zheng-Yi Chen, DPhil, and Qin Liu, MD, PhD, are combining forces to combat a rare disease that leads to blindness and deafness. Watch this video of Read More
Ocular Genomics Institute Scientists publish large Gene-Wide Association Study of Glaucoma
March 2, 2021Janey Wiggs Ayellet Segre Janey Wiggs, MD, Ph.D., Ocular Genomics Institute Associate Director, Chief of Ophthalmology Clinical Research at Mass Eye and Ear, and the Paul Austin Chandler Professor of Ophthalmology and Vice Chair of Clinical Research at Harvard Medical School, and Ayellet Segre, genetic biostatistician, Ocular Genomics... Read More
First proof of concept for a therapy to treat patients with NMNAT1-associated disease
September 16, 2020Molecular Therapy: Methods & Clinical Development Vol. 18 September 2020 ª 2020 Authors from the Ocular Genomics Institute and Grousebeck Gene therapy Center have published the first proof of concept for a therapy to treat patients with NMNAT1-associated disease. No treatment is available for nicotinamide mononucleotide... Read More
Recent OGI Publications
June 12, 2020AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE... Read More
CRISPR trick in mice points the way to possible treatments for inherited diseases
March 8, 2018With the power of the genome-editing tool CRISPR on display, scientists around the world have been hard at work in recent years — developing CRISPR-based therapies that may one day edit disease-causing mutations in our DNA for the treatment of inherited disorders. But there are still great challenges with this powerful tool, and... Read More
Ocular Genomics Institute researchers find a connection between changes in the extracellular matrix of Bruch’s membrane and the activation of the Alternative Complement Pathway in Macular Degeneration.
November 3, 2017In a study published online this week in the Human Molecular Genetics journal, Drs. Rosario Fernandez-Godino, Dr. Kinga M. Bujakowska, and Dr. Eric Pierce of the Ocular Genomics Institute at the Massachusetts Eye and Ear, Harvard Medical School reported the remarkable finding that the formation of basal deposits in macular degeneration is... Read More