2019 Annual ASGCT Meeting
The OGI was well represented at the ASGCT meeting with members from the Vandenberghe and Liu labs presenting the work listed below.
Andrea D’Amico, “Long-Term Rescue of Retinal Degeneration in Rho-P23H Knockin Mice via Dual AAV-Medicated Allele-Specific CRISPR-Cas9 Gene Editing” (oral presentation)
Nachi Pendse, “CRISPR/Cas Based Evaluation of the Therapeutic Potential for USH2A Associated Diseases” (oral presentation)
Carmen Unzu, “NGS-Based Multiplexed AAV Library Screening across Species and Preclinical Liver Models” (oral presentation)
Anna Maurer, “Unbiased Proteomic Approach Identifies Novel Cellular Factors involved in Aadeno-Associated Vector Production” (oral presentation)
Amanda Dudek, “AAVR Independent AAV Serotypes Require Neuraminidase 1 and Cathespin A for Cellular Entry” (oral presentation)
Amanda Dudek, “Genome-Wide CRISPR/Cas9 Screening Identifies GPR108 as a Highly Conserved AAV Entry Factor (oral presentation)
Christopher Tipper, “Multiplex and Clonal Assessment of Production Yield of in Silico Designed AncAAVs” (poster)
Pauline Schmit, “Quantifying Correct Packaging in Multiplexed AAV Libraries (poster)
Ana Karla Cepeda Diaz, “Assembly Activating Protein Affects the Association between Ubiquitin and Aden-Associated Virus Viral Proteins” (oral presentation)
Eva Andres -Mateos, “Optimized Surgical Approach Leads to Highly Efficient AAV Gene Transfer to Inner Hair Cells in Rhesus Macaque” (oral presentation)
Weiwei Wang, “Miniaturizing Usher Syndrome Type 2A Gene for Gene Therapy via Cilia Formation Evaluation “(poster)
Eric Zinn, “Decoding AAV through in Silico Design and Multi-Parametric Screening” (poster)
Eric Zinn, CombiAAV enables Rapid Generation of Combinatorially Diverse Barcoded AAV Capsid Libraries (oral presentation)
Ru Xiao, “Utility of Diatomaceous Earth in Lysate Clarification Simplifies AAV Production (oral presentation)