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Precision Medicine at Work
June 18, 2021Precision Medicine at work for patients with Inherited Retinal Disorders https://youtu.be/FXdHVi9szb8 Rachel Huckfeldt, MD, PhD of the Inherited Retinal Disorders (IRD) Service and the Ocular Genomics Institute, speaks about the important collaborations between... Read More
Work by Caitlin Collin & Qin Liu highlighted at ARVO 2021 meeting
June 3, 2021Caitlin CollinQin Liu At the virtual 2021 meeting of the Association for Research in Vision and Ophthalmology (ARVO), Caitlin Collin, PhD, from Mass Eye and Ear (MEE), presented a promising CRISPR/Cas9 gene-editing approach for treating people with autosomal dominant retinitis pigmentosa (adRP) caused by mutations in the gene RP1. The project... Read More
Ground-breaking study to restore vision uses CRISPR technology
May 24, 2021Eric Pierce MD PhDJason Comander MD PhD Mass Eye and Ear is co-leading a new, revolutionary clinical trial that uses CRISPR gene editing to correct a genetic mutation that leads to a form of blindness caused by Leber congenital amaurosis, an inherited retinal disorder. Clinical trial participant Michael Kalberer is the second person in the... Read More
Ocular Genomics Institute Scientists publish large Gene-Wide Association Study of Glaucoma
March 2, 2021Janey WiggsAyellet Segre Janey Wiggs, MD, Ph.D., Ocular Genomics Institute Associate Director, Chief of Ophthalmology Clinical Research at Mass Eye and Ear, and the Paul Austin Chandler Professor of Ophthalmology and Vice Chair of Clinical Research at Harvard Medical School, and Ayellet Segre, genetic biostatistician, Ocular Genomics... Read More
AAVCOVID Vaccine developed by Luk Vandenberghe to start Clinical trials
February 10, 2021Associate OGI Director Luk Vandenberghe and University of Pennsylvania gene therapy head James Wilson said primate safety and efficacy tests have proven promising for their single-dose candidate, targeted for room-temperature storage. The Bill & Melinda Gates Foundation has awarded the researchers up to $2.1 million to move the vaccine... Read More
The Genetics of and Genetic Therapies for Inherited Retinal Degenerations
October 22, 2020Eric Pierce MD PhD and OGI director participated in the distinguished speaker lecture series organized by the Center For Translational Vision Research at University of California, Irvine in September 2020. You can watch the lecture below. https://youtu.be/uRyAOKuZ928
Rosario Fernandez Godino awarded grant
October 20, 2020The Global Ophthalmology Awards Program from Bayer has awarded a grant to Rosario Fernandez Godino for her project: Studying the impact of ageing and Bruch’s membrane mechanotransduction in age-related macular degeneration (AMD).This proposal aims to bridge the gaps between normal ageing and RPE/Bruch’s membrane pathology to inform... Read More
2019 Chan Zuckerberg Initiative Seed Network award for the Cell Atlas of the Human Eye
August 16, 2019Dr. Ayellet Segrè is part of a team of investigators awarded a $2 million grant by the Chan Zuckerberg Initiativeto build a cell atlas of the human eye from birth to old age, as part of a global research effort called the Human Cell Atlas,using single cell RNA-sequencing, and to identify gene expression and regulation specific to different cell... Read More
OGI 2019 Summer Outing
August 16, 2019On July 10th staff from all the OGI labs gathered for a scavenger hunt in Kendall Square followed by lunch at Flat Top Johnny’s. Thanks to all who turned out to make this a fun event. Congratulations to Team 3 for winning the scavenger hunt! Here are the photos uploaded during... Read More
Stein Innovation Award
August 16, 2019Eric A. Pierce, MD, PhD, Director of the inherited Disorders Service received the 2019 Stein Innovation Award from Research to Prevent Blindness. The award provides up to $300,000 over three years to support his research investigating extracellular vesicles as potential biomarkers for retinal degenerations.