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Licensing Agreement with Biogen to Develop Treatment for Inherited Retinal Disorder
August 25, 2020Massachusetts Eye and Ear, a member hospital of Mass General Brigham, is entering into an exclusive licensing agreement with Biogen to develop a potential treatment for inherited retinal degeneration due to mutations in the PRPF31 gene, which are among the most common causes for autosomal dominant retinitis pigmentosa. Inherited retinal... Read More
Kinga M. Bujakowska, PhD, Receives RPB International Research Collaborators Award
August 14, 2020Kinga M. Bujakowska, PhD, a molecular geneticist and Assistant Professor of Ophthalmology at Harvard Medical School, has been awarded the Research to Prevent Blindness 2020 RPB International Research... Read More
Genetic Links Between Glaucoma and Alzheimer’s Disease
August 14, 2020New research led by Drs. Janey Wiggs and Milica Margeta (Mass. Eye and Ear), recently published in Read More
Caitlin Collin, PhD, Awarded Knights Templar Eye Foundation Grant
August 14, 2020Mass. Eye and Ear postdoctoral research fellow Caitlin Collin, PhD, was awarded a Career Starter Grant from the Knights Templar Eye Foundation. The grant will provide $70,000 of support for Dr. Collin’s research on the development of gene editing approaches for ABCA4-associated Stargardt disease. The Knights... Read More
Vandenberghe Lab working on SARS-CoV2 vaccine
June 15, 2020Luk Vandenberghe PhD, Assistant Director of the Ocular Genomics Institute, Director of the Grousbeck Gene Therapy Center at Massachusetts Eye and Ear, and Associate Professor of Ophthalmology at Harvard Medical School is leading the work at Massachusetts Eye and Ear and Massachusetts General Hospital in the development of an experimental... Read More
Recent OGI Publications
June 12, 2020AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE... Read More
2019 Chan Zuckerberg Initiative Seed Network award for the Cell Atlas of the Human Eye
August 16, 2019Dr. Ayellet Segrè is part of a team of investigators awarded a $2 million grant by the Chan Zuckerberg Initiativeto build a cell atlas of the human eye from birth to old age, as part of a global research effort called the Human Cell Atlas,using single cell RNA-sequencing, and to identify gene expression and regulation specific to different cell... Read More
OGI 2019 Summer Outing
August 16, 2019On July 10th staff from all the OGI labs gathered for a scavenger hunt in Kendall Square followed by lunch at Flat Top Johnny’s. Thanks to all who turned out to make this a fun event. Congratulations to Team 3 for winning the scavenger hunt! Here are the photos uploaded during... Read More
Stein Innovation Award
August 16, 2019Eric A. Pierce, MD, PhD, Director of the inherited Disorders Service received the 2019 Stein Innovation Award from Research to Prevent Blindness. The award provides up to $300,000 over three years to support his research investigating extracellular vesicles as potential biomarkers for retinal degenerations.
Jason Comander receives award at HMS 2019 Alumni meeting
August 16, 2019
2019 Annual ASGCT Meeting
May 22, 2019The OGI was well represented at the ASGCT meeting with members from the Vandenberghe and Liu labs presenting the work listed below. ASCGT 2019 Andrea D'Amico, "Long-Term Rescue of Retinal Degeneration in Rho-P23H Knockin Mice via Dual AAV-Medicated Allele-Specific CRISPR-Cas9 Gene Editing" (oral presentation) Nachi Pendse, "CRISPR/Cas... Read More