Extracellular Vesicle RNAs as Biomarkers for Inherited Retinal Degenerations
March 27, 2025Inherited retinal degenerations (IRD) are important causes of vision loss due to progressive dysfunction of photoreceptor and retinal pigment epithelial (RPE) cells of the retina. Pathogenic variants in the PRPF31 gene are among the most common causes of dominant IRD. In a recent study, published in Molecular Therapy: Methods &... Read More
BRILLIANCE Trial shows CRISPR Gene Editing Found Safe and Effective for Treating Patients with rare genetic disorder.
March 25, 2025OGI members Eric Pierce MD, PhD and Read More
Dr. Lizzy Rossin of the OGI profiled in Retina Today
March 13, 2025WHERE IT ALL BEGAN I grew up in Newton, Massachusetts, and went to the Winsor School for high school. When I was younger, I was always interested in math and science. I loved physics and ultimately decided to get my undergraduate degree in engineering at the University of Pennsylvania before deciding to apply my interest in quantitative... Read More
Increased Ethnic Diversity Needed in Genetic Studies of Primary Open Angle Glaucoma
March 10, 2025A study by OGI members Inas Aboobakar MD, Ayellet Segre, PhD and Janey Wiggs, MD. PhD used cross ancestry genome-wide association studies to identify novel risk loci as well as differences in known loci across ancestries highlighting the need for increased ethnic diversity in glaucoma genetic studies. The paper was selected for presentation... Read More