Associate Director

xiaowu gai

Dr. Gai graduated from Peking University in 1991 with a bachelor’s degree in Environmental Biology and Ecology and received a Master’s degree in genetics from Chinese Academy of Sciences in 1994. He obtained his PhD degree in molecular genetics in 1999 from Iowa State University with a research excellence award. Prior to joining the faculty of Department of Ophthalmology at Massachusetts Eye and Ear Infirmary (MEEI), Dr. Gai was the Director of Biomedical Informatics at Loyola University Stritch School of Medicine, and an Assistant Professor of Molecular Pharmacology and Therapeutics. Dr. Gai currently serves as the Director of Bioinformatics at MEEI and directs the MEEI Bioinformatics Center (MBC). He is also an Associate Director and the Director of Bioinformatics for the Ocular Genomics Institute.

Dr. Gai is a human geneticist and a bioinformatician with primary research interest in understanding genetic variations and how they are related to human diseases using bioinformatics and genomics methodologies. With genotyping technologies and developing bioinformatics tools as needed, Dr. Gai identified CNVs that are associated with several genetic disorders as well as complex diseases such as ADHD and autism. Recently, Dr. Gai has been developing and applying bioinformatics tools for whole-exome (WES) data analysis. He has discovered a number of novel disease genes and published two of them so far: NMNAT1 for Leber congenital amaurosis and FBLX4 for mitochondrial disease.

Dr. Gai’s research is also translational. A primary research goal for Dr. Gai is to improve patient care through genomics and bioinformatics means, including but not limited to improved disease diagnosis.

Dr. Gai is currently hiring an intern, a post doc and a bioinformaticist.

Please click the links for more info.


Summer 2014 Intern

Post doctoral Position

Contact Info:

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